This can happen to the K1600 if the throttle lost communication with the computer. In my case the dealer cleaned out each and every pin on the connector cable. There was a protective coating on the pins to prevent oxidation applied from the manufacturer due to the long wait prior to actual assembly. BMW was supposed clean the pins during the assembly process but some apparently were not. This can cause an intermittent contact and will cause a computer fault code about the loss of communication with the throttle. In my case it was under warranty but highly inconvenient. 20K miles later still good to go.Forgive my ignorance as I'm new to BMW Motorrad and also not familiar with the Bren tune, but such an issue of complete throttle loss doesn't/wouldn't happen on a stock K1600 WITHOUT the Bren tune, correct? To me that automatically sounds "tune" related. Some of the comments re: drive by wire...the engine is great but nothing else, ETC, Really? I know anything/everything CAN happen, but this can't be anything common with any motorcycle...at least I wouldn't think so. Good luck finding out.